PAI-1

PAI-1 is a plasminogen activator inhibitor. PAI-1 is a member of the Ser Protease inhibitor superfamily with antiprotease activity. PAI-1 is the main physiological inhibitor of tissue-type (tPA) and urokinase-type (uPA) plasminogen activators (PAs) [1].

Product Specifications

CAS Number

[139446-70-1]

UNSPSC

12352209

Target

Ser/Thr Protease

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

[H]N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)C)=O)CCSC)=O)=O)C

Molecular Formula

C27H47N9O9S

Molecular Weight

673.78

References & Citations

[1]Tang Z, et al. Surface immobilization of a protease through an inhibitor-derived affinity ligand: a bioactive surface with defensive properties against an inhibitor. Chem Commun (Camb) . 2015 Sep 28;51 (75) :14263-6.