Prion Protein (118-135), human

Prion Protein (118-135), human is the 118-135 fragment of human prion protein. Prion Protein (118-135), human induces Apoptosis. Prion Protein (118-135), human stimulates caspase-3 and -9 activities. Prion Protein (118-135), human is cytotoxic to retinal neurons. Prion Protein (118-135), human exerts neurotoxic effects[1].

Product Specifications

CAS Number

[202121-03-7]

UNSPSC

12352209

Target

Apoptosis; Caspase

Related Pathways

Apoptosis

Field of Research

Neurological Disease

Smiles

O=C(NCC(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(NCC(NCC(N[C@@H](CC(C)C)C(NCC(NCC(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCSC)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C68H112N18O22S2

Molecular Weight

1597.85

References & Citations

[1]Chabry J, et al. In vivo and in vitro neurotoxicity of the human prion protein (PrP) fragment P118-135 independently of PrP expression. J Neurosci. 2003 Jan 15;23 (2) :462-9.