Prion Protein (118-135), human
Prion Protein (118-135), human is the 118-135 fragment of human prion protein. Prion Protein (118-135), human induces Apoptosis. Prion Protein (118-135), human stimulates caspase-3 and -9 activities. Prion Protein (118-135), human is cytotoxic to retinal neurons. Prion Protein (118-135), human exerts neurotoxic effects[1].
Product Specifications
CAS Number
202121-03-7
UNSPSC
12352209
Target
Apoptosis; Caspase
Related Pathways
Apoptosis
Field of Research
Neurological Disease
Smiles
O=C(NCC(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(NCC(NCC(N[C@@H](CC(C)C)C(NCC(NCC(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCSC)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N
Molecular Formula
C68H112N18O22S2
Molecular Weight
1597.85
References & Citations
[1]Chabry J, et al. In vivo and in vitro neurotoxicity of the human prion protein (PrP) fragment P118-135 independently of PrP expression. J Neurosci. 2003 Jan 15;23 (2) :462-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Caspase 3; Caspase 9
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