Boc-Ala-Gly-Pro-Arg-AMC

Boc-Ala-Gly-Pro-Arg-AMC is a synthetic fluorescent substrate, widely used for the detection of protease activity. Boc-Ala-Gly-Pro-Arg-AMC can be used to detect the activity of serine proteases and the oligopeptide enzyme B of Trypanosoma brucei[1][2].

Product Specifications

CAS Number

[118850-78-5]

UNSPSC

12352209

Target

Fluorescent Dye; Ser/Thr Protease

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Infection; Metabolic Disease

Smiles

CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C(CNC([C@H](C)NC(OC(C)(C)C)=O)=O)=O)=O)=O)C=C1O3)=CC3=O

Molecular Formula

C31H44N8O8

Molecular Weight

656.73

References & Citations

[1]Morty RE, et al. Oligopeptidase B from Trypanosoma brucei, a new member of an emerging subgroup of serine oligopeptidases. J Biol Chem. 1999 Sep 10;274 (37) :26149-56. |[2]Imada T, et al. Identification of a peptidase which processes atrial natriuretic factor precursor to its active form with 28 amino acid residues in particulate fractions of rat atrial homogenate. Biochem Biophys Res Commun. 1987 Mar 13;143 (2) :587-92.