KRAS G12C Peptide (TFA)

KRAS G12C Peptide TFA is the trifluoroacetate salt of KRAS G12C Peptide (HY-P11357) . KRAS G12C Peptide is a specific peptide derived from the Kirsten rat sarcoma virus (KRAS) gene carrying the G12C oncogenic mutation. KRAS G12C Peptide induces responses like IFN-γ secretion and cytotoxicity. KRAS G12C Peptide can be used for the study of immune responses against KRAS G12C-mutant tumors[1].

Product Specifications

UNSPSC

12352209

Target

IFNAR

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Purity

95.15

Smiles

O=C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(NCC(N[C@@H](C)C(N[C@@H](CS)C(NCC(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N.OC(C(F)(F)F)=O.[x]

Molecular Formula

C38H69N11O11S.xC2HF3O2

Molecular Weight

888.09 (free base)

References & Citations

[1]Zheng W, et al. Exploring the therapeutic potential of precision T-Cell Receptors (TCRs) in targeting KRAS G12D cancer through in vitro development. Oncol Res. 2024 Nov 13;32 (12) :1837-1850.