Verlamelin A
Verlamelin A is a macrocyclic depsipeptide with antifungal and antiviral activity. Verlamelin A shows antifungal activity toward Aspergillus versicolor and Curvularia australiensis and also has antiviral activity toward HSV-1 (IC50 = 16.7 μM) . Verlamelin A is isolated from the entomopathogenic fungus Lecanicillium sp. Verlamelin A is useful for antifungal and antiviral research[1][2][3].
Product Specifications
CAS Number
1619244-34-6
UNSPSC
12352209
Target
Fungal; HSV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C1[C@@]2([H])N(C([C@H](NC([C@@](NC(CCC[C@@H](OC([C@@H](NC([C@H](NC([C@@H](N1)CCC(N)=O)=O)CC3=CC=C(C=C3)O)=O)C(C)C)=O)CCCCCCCCC)=O)([H])[C@H](O)C)=O)C)=O)CCC2
Molecular Formula
C45H71N7O11
Molecular Weight
886.09
References & Citations
[1]Ishidoh K, et al. Cyclic lipodepsipeptides verlamelin A and B, isolated from entomopathogenic fungus Lecanicillium sp. J Antibiot (Tokyo) . 2014 Jun;67 (6) :459-63.|[2]Sun X, et al. Total Synthesis of Verlamelin A and (5R) -Verlamelin A with Antifungal Activity. J Org Chem. 2025 Sep 5;90 (35) :12425-12434.|[3]Liang X, et al. Antifungal and Antiviral Cyclic Peptides from the Deep-Sea-Derived Fungus Simplicillium obclavatum EIODSF 020. J Agric Food Chem. 2017 Jun 28;65 (25) :5114-5121.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
HSV-1
Frequently Asked Questions
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