Microcyclamide

Microcyclamide (Compound 1), a cytotoxic cyclic hexapeptide, is a microbial secondary metabolite. Microcyclamide can be isolated from the cyanobacterium Microcystis aeruginosa. Microcyclamide has moderate cytotoxicity against P388 murine leukemia cells with an IC50 of 1.2 μg/mL. Microcyclamide can be used for cancers research[1].

Product Specifications

CAS Number

[297730-40-6]

UNSPSC

12352209

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(N[C@H](C1=NC(C(N[C@@](C2=NC(C(N3)=O)=CS2)([H])[C@@H](C)CC)=O)=C(O1)C)C)C4=CSC([C@@H]3CC5=CN=CN5C)=N4

Molecular Formula

C26H30N8O4S2

Molecular Weight

582.70

References & Citations

[1]Ishida K, et al. Microcyclamide, a cytotoxic cyclic hexapeptide from the cyanobacterium Microcystis aeruginosa. J Nat Prod. 2000 Sep;63 (9) :1315-7.