Ac-RR-AFC (TFA)
Ac-RR-AFC TFA is a Cathepsin B fluorogenic substrate (Ex=400 nm, Em=505 nm) . Cathepsin B activity in cells lysates is determined by measuring cleavage of Ac-RR-AFC TFA and its cleavage occurs at the RR-AFC amide bond. Ac-RR-AFC TFA can be used for activity assays and mechanistic studies on cathepsin B[1].
Product Specifications
UNSPSC
12352209
Target
Cathepsin; Fluorescent Dye
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Smiles
NC(NCCC[C@H](NC([C@@H](NC(C)=O)CCCNC(N)=N)=O)C(NC1=CC=C(C(C(F)(F)F)=CC(O2)=O)C2=C1)=O)=N.OC(C(F)(F)F)=O
Molecular Formula
C26H33F6N9O7
Molecular Weight
697.59
References & Citations
[1]Zhang X, et al. Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination. J Exp Clin Cancer Res. 2017 Sep 5;36 (1) :118.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Cathepsin B
Frequently Asked Questions
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