ABri
ABri, 34 amino acids long, is an Amyloid subunit with certain degree of N- and C-terminal heterogeneity and no sequence identity to any known amyloid protein. ABri is devoid of glycine, methionine, proline, aspartic acid, tryptophane, tyrosine and glutamine, featuring pyroglutamate at its N-terminus. ABri can be used for cerebral hemorrhages, ischemic infarction and Alzheimer disease research[1].
Product Specifications
CAS Number
241145-90-4
UNSPSC
12352209
Target
Amyloid-β
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease; Cardiovascular Disease
Smiles
O=C(NC(C)C(NC(CO)C(NC(CC(N)=O)C(NC(CS)C(NC(CC1=CC=CC=C1)C(NC(C)C(NC(C(C)CC)C(NC(CCCNC(N)=N)C(NC(CC2=CNC=N2)C(NC(CC3=CC=CC=C3)C(NC(CCC(O)=O)C(NC(CC(N)=O)C(NC(CCCCN)C(NC(CC4=CC=CC=C4)C(NC(C)C(NC(C(C)C)C(NC(CCC(O)=O)C(NC(C(O)C)C(NC(CC(C)C)C(NC(C(C)CC)C(NC(CS)C(NC(CO)C(NC(CCCNC(N)=N)C(NC(C(O)C)C(NC(C(C)C)C(NC(CCCCN)C(NC(CCCCN)C(NC(CC(N)=O)C(NC(C(C)CC)C(NC(C(C)CC)C(NC(CCC(O)=O)C(NC(CCC(O)=O)C(NC(CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(CCC(O)=O)N
Molecular Formula
C173H277N49O53S2
Molecular Weight
3955.48
References & Citations
[1]Ghiso J, et al. Cerebral amyloidosis, amyloid angiopathy, and their relationship to stroke and dementia. J Alzheimers Dis. 2001 Feb;3 (1) :65-73.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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