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ABri

ABri, 34 amino acids long, is an Amyloid subunit with certain degree of N- and C-terminal heterogeneity and no sequence identity to any known amyloid protein. ABri is devoid of glycine, methionine, proline, aspartic acid, tryptophane, tyrosine and glutamine, featuring pyroglutamate at its N-terminus. ABri can be used for cerebral hemorrhages, ischemic infarction and Alzheimer disease research[1].

Product Specifications

CAS Number

241145-90-4

UNSPSC

12352209

Target

Amyloid-β

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease; Cardiovascular Disease

Smiles

O=C(NC(C)C(NC(CO)C(NC(CC(N)=O)C(NC(CS)C(NC(CC1=CC=CC=C1)C(NC(C)C(NC(C(C)CC)C(NC(CCCNC(N)=N)C(NC(CC2=CNC=N2)C(NC(CC3=CC=CC=C3)C(NC(CCC(O)=O)C(NC(CC(N)=O)C(NC(CCCCN)C(NC(CC4=CC=CC=C4)C(NC(C)C(NC(C(C)C)C(NC(CCC(O)=O)C(NC(C(O)C)C(NC(CC(C)C)C(NC(C(C)CC)C(NC(CS)C(NC(CO)C(NC(CCCNC(N)=N)C(NC(C(O)C)C(NC(C(C)C)C(NC(CCCCN)C(NC(CCCCN)C(NC(CC(N)=O)C(NC(C(C)CC)C(NC(C(C)CC)C(NC(CCC(O)=O)C(NC(CCC(O)=O)C(NC(CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(CCC(O)=O)N

Molecular Formula

C173H277N49O53S2

Molecular Weight

3955.48

References & Citations

[1]Ghiso J, et al. Cerebral amyloidosis, amyloid angiopathy, and their relationship to stroke and dementia. J Alzheimers Dis. 2001 Feb;3 (1) :65-73.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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