SFTI-KLK7

SFTI-KLK7 is a KLK7 inhibitor, with Ki 0.14 nM[1].

Product Specifications

UNSPSC

12352209

Target

Others

Related Pathways

Others

Field of Research

Inflammation/Immunology

Smiles

O=C(N[C@@H](CCCCN)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)NC3=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N5[C@@H](CCC5)C(N6[C@@H](CCC6)C(N[C@H]3[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O)CN

Molecular Formula

C70H103N17O18S2

Molecular Weight

1534.80

References & Citations

[1]de Veer SJ, Furio L, et al. Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum. J Invest Dermatol. 2017 Feb;137 (2) :430-439.