SFTI-KLK5

SFTI-KLK5 is a KLL5 inhibitor with a Ki value of 5.1 nM[1].

Product Specifications

UNSPSC

12352209

Target

Others

Related Pathways

Others

Field of Research

Inflammation/Immunology

Smiles

O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CSSC[C@H](NC([C@@H]2[C@H](CC)C)=O)C(N[C@H](C(N3CCC[C@H]3C(N[C@H](C(O)=O)CC(N)=O)=O)=O)CC(N)=O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CC4=CC=C(C=C4)O)C(N5[C@@H](CCC5)C(N6[C@@H](CCC6)C(N2)=O)=O)=O)=O)=O)=O)=O)=O)CN

Molecular Formula

C68H98N20O21S2

Molecular Weight

1595.76

References & Citations

[1]de Veer SJ, et al. Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum. J Invest Dermatol. 2017 Feb;137 (2) :430-439.