MC4-NN2-0453
MC4-NN2-0453, a α-MSH analog, is a selective MC4R agonist. MC4-NN2-0453 can be used for obesity research[1].
Product Specifications
CAS Number
[1228015-10-8]
UNSPSC
12352209
Target
Melanocortin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
99.15
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CNC(CN(CC(O)=O)CC(O)=O)=O)C(N[C@@H](CCCC)C(N[C@@H](CCC1=O)C(N2[C@@H](CC(C2)O)C(N[C@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CNC5=CC=CC=C45)C(N[C@@H](CCCCN1)C(N)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](NC([C@@H](NC([C@@H](NC(CNC(COCCOCCNC(CCCCCCCCCCCCCCCC6=NN=NN6)=O)=O)=O)CO)=O)CCC(N)=O)=O)CC7=CNC=N7
Molecular Formula
C96H146N28O25
Molecular Weight
2092.36
References & Citations
[1]Royalty JE, et al. Investigation of safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of a long-acting α-MSH analog in healthy overweight and obese subjects. J Clin Pharmacol. 2014 Apr;54 (4) :394-404.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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