Tismanitin maleimide
Tismanitin maleimide (pamlectabart tismanitin; HDP-101) is a linker-cargo component of an antibody-drug conjugate (ADC) . Tismanitin maleimide is covalently bound to a monoclonal antibody (mAb) through a cleavable linker, forming a targeted anti-cancer therapy. Tismanitin maleimide can be used for research on multiple myeloma[1].
Product Specifications
CAS Number
[2311860-86-1]
Product Name Alternative
Pamlectabart tismanitin ; HDP-101
UNSPSC
12352209
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
O=C(C=CC1=O)N1CCC(N[C@@](C(N[C@@](C(NC2=CC=C(CNC(C[C@H](NC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H]3N4C[C@@H](C3)O)=O)[C@H]([C@H](CO)O)C)=O)CC5=C6NC7=C5C=CC=C7)=O)=O)[C@H](CC)C)=O)=O)CS6=O)=O)C4=O)=O)C=C2)=O)([H])C)=O)([H])C(C)C)=O
Molecular Formula
C61H80N14O18S
Molecular Weight
1329.44
References & Citations
[1]Butler MS, et al. Natural product-derived compounds in clinical trials and drug approvals. Nat Prod Rep. 2025 Sep 9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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