Cyclic peptide P1-1
Cyclic peptide P1-1 is a high-potent GPR55 antagonist. Cyclic peptide P1-1 antagonizes GPR55 and suppresses collagen secretion. Cyclic peptide P1-1 reduces ROS production, attenuates ER stress, and inhibits mitochondria-associated Apoptosis. Cyclic peptide P1-1 inhibits the expression of α-SMA and COL1α. Cyclic peptide P1-1 ameliorates CCl4 -induce and MCD-diet-induce acute liver inflammation and fibrosis[1].
Product Specifications
UNSPSC
12352209
Target
Apoptosis; Collagen; GPR55; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Cytoskeleton; GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Metabolic Disease
Smiles
Molecular Formula
C40H70N12O13S2
Molecular Weight
991.19
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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