DOTA-FAPT
DOTA-FAPT is a novel targeting FAP tracer. DOTA-FAPT can be radiolabeled with gallium-68 and lutetium-177. DOTA-FAPT can be used for PET imaging studies of cancer-associated fibroblasts[1].
Product Specifications
UNSPSC
12352209
Target
Radionuclide-Drug Conjugates (RDCs)
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
O=C(COCCOCCNC([C@H](CC(O)=O)NC([C@H](CC(O)=O)NC([C@@H](NC(CN1CCN(CCN(CCN(CC1)CC(O)=O)CC(O)=O)CC(O)=O)=O)CCC(N[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(C)=O)=O)=O)=O)=O)N3CCN(CCCOC4=CC=C(C5=C4)N=CC=C5C(NCC(N6CC(F)(C[C@]6(C#N)[H])F)=O)=O)CC3
Molecular Formula
C67H96F2N16O26
Molecular Weight
1579.57
References & Citations
[1]Huang J, et al. 68Ga/177Lu-Labeled Theranostic Pair for Targeting Fibroblast Activation Protein with Improved Tumor Uptake and Retention. J Med Chem. 2024 Oct 10;67 (19) :17785-17795.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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