RI-18

RI-18 is an antimicrobial peptide. RI-18 exhibits high affinity for bacterial plasma membranes, inducing rapid membrane permeabilization and rupture. RI-18 exhibits potent antimicrobial activity against bacteria in planktonic and biofilmforms[1].

Product Specifications

UNSPSC

12352209

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

Molecular Formula

C102H190N32O19

Molecular Weight

2168.80

References & Citations

[1]Wu Z, et al. Development of α-Helical Antimicrobial Peptides with Imperfect Amphipathicity for Superior Activity and Selectivity. J Med Chem. 2024 Nov 14;67 (21) :19561-19572.