NOTA-SFCVHEM

NOTA-SFCVHEM can be activated by CTB. NOTA-SFCVHEM can be used to prepare PET tracer. NOTA-SFCVHEM has good stability, low toxicity, high tumor selectivity, and low liver accumulation[1].

Product Specifications

UNSPSC

12352209

Target

Others

Related Pathways

Others

Field of Research

Cancer

Smiles

O=C(CN1CCOCC1)N[C@@H](CC2=CNC=N2)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(N[C@@H](C(N[C@H](C(NCC(NCC5=CC=C(C(NCC6=CC=C(C=C6)C(NC(C(NC7=CC8=C(C=C7)N=C(C#N)S8)=O)CCCCNC(CN9CCN(CCN(CC9)CC(O)=O)CC(O)=O)=O)=O)=O)C=C5)=O)=O)CSSCC)=O)CCCNC(N)=O)=O)C(C)C)=O)=O)=O)=O)=O)=O

Molecular Formula

C99H133N29O27S3

Molecular Weight

2257.49

References & Citations

[1]Li H, et al. Positron Emission Tomography Imaging of Cathepsin B in Tumors with Activable Small Molecule Tracers. J Med Chem. 2024 Dec 12;67 (23) :21292-21302.