Lipo-PtIV-R8K

Lipo-PtIV-R8K is a nuclear targeting peptide containing R8K. Lipo-PtIV-R8K is a lipid PtIV prodrug amphiphilic molecule that can self assemble to form nanoparticles. Lipo-PtIV-R8K can be used in the research of cancer such as breast cancer[1].

Product Specifications

UNSPSC

12352209

Target

Others

Related Pathways

Others

Field of Research

Cancer

Smiles

CCCCCCCCCCCCCCCCNC([O-][Pt+4]([NH3])([Cl-])([Cl-])([O-]C(CCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[NH3])=O

Molecular Formula

C75H153Cl2N37O15Pt

Molecular Weight

2079.25

References & Citations

[1]Wei D, et al. Nuclear-Targeting Lipid PtIV Prodrug Amphiphile Cooperates with siRNA for Enhanced Cancer Immunochemotherapy by Amplifying Pt-DNA Adducts and Reducing Phosphatidylserine Exposure. J Am Chem Soc. 2024 Jan 10;146 (1) :1185-1195.