D2A21 (TFA)

D2A21 TFA is an antimicrobial peptide with significant antimicrobial activity against Pseudomonas and bactericidal effect on burn scabs. D2A21 TFA has antitumor activity and can be used in prostate cancer research[1][2].

Product Specifications

UNSPSC

12352209

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Purity

95.35

Smiles

OC([C@H](CC1=CC=CC=C1)NC([C@H](C)NC([C@H](CC2=CC=CC=C2)NC([C@H](C)NC([C@H](CC3=CC=CC=C3)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CC4=CC=CC=C4)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CC5=CC=CC=C5)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C)NC([C@@H](N)CC6=CC=CC=C6)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)=O)=O)CC8=CC=CC=C8)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F.[x]

Molecular Formula

C144H212N32O24.xC2HF3O2

Molecular Weight

2775.42 (free base)

References & Citations

[1]Chalekson CP, et al. Improvement in burn wound infection and survival with antimicrobial peptide D2A21 (Demegel) . Plast Reconstr Surg. 2002 Apr 1;109 (4) :1338-43.|[2]Arlotti JA, et al. Efficacy of a synthetic lytic peptide in the treatment of prostate cancer. Urol Oncol. 2001 May;6 (3) :97-102.