AR-23

AR-23 is a melittin-related antimicrobial peptide from Rana tagoi. AR-23 exhibits broad-spectrum growth inhibitory activity against aerobic bacteria, the opportunistic yeast pathogen Candida albicans and clinical isolates of Methicillin (HY-121544) -resistant Staphylococcus aureus (MRSA) . AR-23 can be used for antimicrobial research[1].

Product Specifications

CAS Number

[590424-23-0]

UNSPSC

12352209

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C111H191N31O27

Molecular Weight

2391.90

References & Citations

[1]Urbán E, et al. Activities of four frog skin-derived antimicrobial peptides (temporin-1DRa, temporin-1Va and the melittin-related peptides AR-23 and RV-23) against anaerobic bacteria. Int J Antimicrob Agents. 2007 Mar;29 (3) :317-21.