ChMAP-28
ChMAP-28 is an antimicrobial peptide. ChMAP-28 can be derived from goat Capra hircus. ChMAP-28 can initiate necrotic death. ChMAP-28 is effective in killing many bacteria, including strains resistant to Polymyxin and Meropenem. ChMAP-28 shows antitumor activity against acute promyelocytic leukemia, epidermoid carcinoma, melanoma, breast adenocarcinoma[1][2].
Product Specifications
UNSPSC
12352209
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Smiles
O=C(NC(CCCNC(N)=N)C(NC(CC1=CC=CC=C1)C(NC(CCCCN)C(NC(CCCNC(N)=N)C(NC(CC2=CC=CC=C2)C(NC(CCCNC(N)=N)C(NC(CCCCN)C(NC(CCCCN)C(NC(CC(C)C)C(NC(CCCCN)C(NC(CCCNC(N)=N)C(NC(CC(C)C)C(NC(CC3=CNC4=CC=CC=C34)C(NC(CC5=CNC=N5)C(NC(CCCCN)C(NC(C(C)C)C(NCC(N6C(CCC6)C(NC(CC7=CC=CC=C7)C(NC(C(C)C)C(NCC(N8[C@@H](CCC8)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CC9=CNC=N9)C(N[C@@H](CC%10=CC=C(C=C%10)O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN
Molecular Formula
C163H255N49O29
Molecular Weight
3365.08
References & Citations
[1]Emelianova AA, et al. Anticancer Activity of the Goat Antimicrobial Peptide ChMAP-28. Front Pharmacol. 2018 Dec 21;9:1501. |[2]Panteleev PV, et al. Combined Antibacterial Effects of Goat Cathelicidins With Different Mechanisms of Action. Front Microbiol. 2018 Nov 30;9:2983.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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