Coccinin

Coccinin is an antifungal peptide. Coccinin can be purified from the seeds of large scarlet runner beans. Coccinin inhibits HIV-1 reverse transcriptase. Coccinin shows antifungal activity against M. arachidicola, F. oxysporum, P. piricola, B. cinerea, C. comatus and R. solani, with IC50s of 75, 81, 89, 109, 122 and 134 μM, respectively[1].

Product Specifications

CAS Number

[1177990-16-7]

UNSPSC

12352209

Target

Fungal; HIV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N

Molecular Formula

C50H79N13O20

Molecular Weight

1182.24

References & Citations

[1]Ngai PH, et al. Coccinin, an antifungal peptide with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from large scarlet runner beans. Peptides. 2004 Dec;25 (12) :2063-8.