Cr-ACP1

Cr-ACP1 is an anti-cancerous peptide. Cr-ACP1 binds to DNA, inducing cell cycle arrest in the G0-G1 phase, leading to the initiation of Apoptosis mechanisms. Cr-ACP1 exhibits anticancer effects against colon cancer and epidermoid carcinoma[1][2].

Product Specifications

CAS Number

[2493968-50-4]

UNSPSC

12352209

Target

Apoptosis; DNA Alkylator/Crosslinker

Related Pathways

Apoptosis; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C50H71N11O14

Molecular Weight

1050.16

References & Citations

[1]Prabhu S, et al. Anionic antimicrobial and anticancer peptides from plants. Critical reviews in plant sciences, 2013, 32 (5) : 303-320. |[2]Shah P, et al. The proteome targets of intracellular targeting antimicrobial peptides. Proteomics. 2016 Apr;16 (8) :1225-37.