Sulfated sulfakinin

Sulfated sulfakinin is a Sulfakinin receptor (SKR) activator with EC50s of 1.6 and 5.4 nM for Tribolium castaneumTc TcSKR1 and TcSKR2, respectively. SKRs are G-protein-coupled receptors (GPCRs) that interact with sulfakinins to modulate diverse biological processes. Sulfated sulfakinin can be used for tho control of pest insects research[1].

Product Specifications

CAS Number

[172430-35-2]

UNSPSC

12352209

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=C(C=C1)OS(=O)(O)=O)C(NCC(N[C@@H](CC2=CNC=N2)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC3=CC=CC=C3)C(N)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC4=CC=CC=C4)N

Molecular Formula

C54H71N15O17S2

Molecular Weight

1266.36

References & Citations

[1]Yu N, et al. Development of cell-based bioassay with Sf9 cells expressing TcSKR1 and TcSKR2 and differential activation by sulfated and non-sulfated SK peptides. Peptides. 2014 Mar;53:238-42.ptides.