Human Defensin-5 (1-9)

Human Defensin-5 (1-9) is an orally active antimicrobial peptide. Human Defensin-5 (1-9) can inhibit metabolic disorders induced by Western-style diet (WSD) or Western-style diet with fructose (WSDF) . Human Defensin-5 (1-9) enhances intestinal barrier function by upregulating the gene expression of ileal tight junction protein and mucins. Human Defensin-5 (1-9) can be used for the study of obesity and related metabolic diseases[1].

Product Specifications

UNSPSC

12352209

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection; Metabolic Disease

Smiles

O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CS)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CS)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C40H68N16O12S2

Molecular Weight

1029.20

References & Citations

[1]Filipe Rosa L, et al. Human α-Defensin 51-9 and Human β-Defensin 2 Improve Metabolic Parameters and Gut Barrier Function in Mice Fed a Western-Style Diet. Int J Mol Sci. 2023 Sep 9;24 (18) :13878.