Latarcin 2a

Latarcin 2a is a linear cationic antibacterial peptide derived from the venom of the spider Lachesana tarabaevi, with broad-spectrum antibacterial activity. Latarcin 2a has a MIC of 0.5 μM for both Bacillus subtilis and Escherichia coli. Latarcin 2a’s dimer form enhances activity. Latarcin 2a is often used in the research of infectious conditions[1].

Product Specifications

CAS Number

[910239-76-8]

UNSPSC

12352209

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=CC=C1)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CC=CC=C2)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CC4=CNC=N4)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN

Molecular Formula

C136H229N41O29

Molecular Weight

2902.53

References & Citations

[1]Shlyapnikov YM, et al. Bacterial production of latarcin 2a, a potent antimicrobial peptide from spider venom. Protein Expr Purif. 2008 Jul;60 (1) :89-95.