LDKA
LDKA is a helical membrane-active antibacterial peptide. LDKA forms an ensemble of pores of different sizes. LDKA has antibacterial activity against both Gram-positive (S. aureus) and Gram-negative (E. coli and P. aeruginosa) bacteria in a nutrient-rich medium, with MICs in the 10-70 μM range[1].
Product Specifications
CAS Number
[2243297-90-5]
UNSPSC
12352209
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](C)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN
Molecular Formula
C68H124N16O17
Molecular Weight
1437.81
References & Citations
[1]Chen CH, et al. Simulation-Guided Rational de Novo Design of a Small Pore-Forming Antimicrobial Peptide. J Am Chem Soc. 2019 Mar 27;141 (12) :4839-4848.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P11135/
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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