RFQF4

RFQF4 is a nanonet-forming peptide and antibacterial agent. RFQF4 exhibits excellent bacterial capture capability coupled with moderate antibacterial activity. RFQF4 shows bactericidal activity against E. coli, S. typhimurium, S. aureus, L. monocytogenes, and S. epidermidis (IC50: 4.89-21.85 μM) [1].

Product Specifications

UNSPSC

12352209

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC7=CC=CC=C7)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC8=CC=CC=C8)C(NCC(N[C@@H](CO)C(NCC(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N9[C@@H](CCC9)C(N%10[C@@H](CCC%10)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

Molecular Formula

C161H232N50O34

Molecular Weight

3411.88

References & Citations

[1]Gao N, et al. Biomimetic Peptide Nanonets: Exploiting Bacterial Entrapment and Macrophage Rerousing for Combatting Infections. ACS Nano. 2024 Sep 17;18 (37) :25446-25464.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported