Metchnikowin

Metchnikowin is a fruit fly antimicrobial peptide rich in proline, with dual antibacterial and antifungal activities. Metchnikowin can be independently regulated by TOLL and IMD pathways. Metchnikowin is often used in the research of infectious conditions[1].

Product Specifications

CAS Number

[175280-86-1]

UNSPSC

12352209

Target

Bacterial; Fungal

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CCC(N)=O)C(NCC(N2[C@@H](CCC2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(N4[C@@H](CCC4)C(N[C@@H](CO)C(N5[C@@H](CCC5)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CC(N)=O)C(N7[C@@H](CCC7)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(N)=O)C(N8[C@@H](CCC8)C(N[C@@H](CCCNC(N)=N)C(N9[C@@H](CCC9)C(NCC(N%10[C@@H](CCC%10)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC%11=CC=C(C=C%11)O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC%12=CNC=N%12)N

Molecular Formula

C137H201N43O36

Molecular Weight

3026.33

References & Citations

[1]Levashina EA, et al. Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin. J Mol Biol. 1998 May 8;278 (3) :515-27.