PA2-GNU7
PA2-GNU7 is an antimicrobial peptide (AMP) . PA2-GNU7 exhibits potent antimicrobial activity with minimal inhibitory concentration (MIC) against P. aeruginosa, E. coli, S. typhimurium, S. aureus, and C. albicans are 2 μM, 1 μM, 2 μM, 2 μM, and 8 μM, respectively. PA2-GNU7 rapidly and selectively kills Pseudomonas aeruginosa without affecting other commensal bacteria. PA2-GNU7 significantly improves survival of mice infected with P. aeruginosa. PA2-GNU7 can be used for the research and development of therapeutic agents against MDR Pseudomonas aeruginosa infections[1].
Product Specifications
CAS Number
2387505-19-1
UNSPSC
12352209
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NC(CCC(N)=O)C(NC(CCCNC(N)=N)C(NC(CCCCN)C(NC(CC(C)C)C(NC(C)C(NC(C)C(NC(CCCCN)C(NC(CC(C)C)C(NC(C(O)C)C(NC(CO)C(NC(CCCCN)C(NCC(NCC(NCC(NC(CCCNC(N)=N)C(NC(CC(C)C)C(NC(CC(C)C)C(NC(CCCNC(N)=N)C(N1C(CCC1)C(NC(CC(C)C)C(N[C@H](CC(C)C)C(NC(CCC(N)=O)C(N[C@H](CC(C)C)C(NC(CC(C)C)C(N[C@H](CCCCN)C(NC(CCC(N)=O)C(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(CO)N
Molecular Formula
C150H276N50O37
Molecular Weight
3372.11
References & Citations
[1]Kim H, et al. Development of a novel hybrid antimicrobial peptide for targeted killing of Pseudomonas aeruginosa. Eur J Med Chem. 2020 Jan 1;185:111814.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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