Xentry
Xentry is a cell-penetrating peptide (CCP) consisting of only 7 amino acids of hepatitis B virus: LCLRPVG. Xentry-linked anti-B-raf antibodies and siRNAs demonstrates the capability to kill B-raf-dependent melanoma cells. Xentry alone or conjugated to β-galactosidase leads to its delivery to most tissues in mice, except circulating blood cells. Xentry can be used for the delivery of large molecules (antibodies, siRNA, enzymes) [1].
Product Specifications
CAS Number
1352335-71-7
UNSPSC
12352209
Target
HBV
Related Pathways
Anti-infection
Field of Research
Cancer
Smiles
O=C(N[C@@H](CS)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(NCC(O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N
Molecular Formula
C33H60N10O8S
Molecular Weight
756.96
References & Citations
[1]Montrose K, et al. Xentry, a new class of cell-penetrating peptide uniquely equipped for delivery of drugs. Sci Rep. 2013;3:1661.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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