Oncocin

Oncocin is an antibacterial peptide. It belongs to proline-rich antimicrobial peptides (PrAMPs) . Oncocin works against Gram-negative bacteria. It has MIC values of 0.125-8 μg/mL for 34 strains and clinical isolates of Enterobacteriaceae and nonfermenters. Oncocin binds to the substrate-binding domain of the chaperone DnaK. The binding has dissociation constants in the micromolar range. This binding causes protein misfolding and aggregation and the bacteria death[1][2].

Product Specifications

CAS Number

[1235497-90-1]

UNSPSC

12352209

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

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