LR-17
LR-17 (TLT-1 (94-110) ), a 17-aa peptide, is a TREM-1 inhibitor. LR-17 shows anti-inflammatory effects that can reduce the secretion of pro-inflammatory cytokines induced by Lipopolysaccharides (HY-D1056) (LPS) . LR-17 can be used for the study of sepsis[1].
Product Specifications
CAS Number
[1256099-50-9]
Product Name Alternative
TLT-1 (94-110)
UNSPSC
12352209
Target
TREM receptor
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
97.52
Smiles
OC(C=C1)=CC=C1C[C@@H](C(NCC(N[C@@H](CS)C(N[C@@H](CCSC)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](C)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CCC(O)=O)NC(CNC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CCC(N)=O)NC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C74H115N21O30S2
Molecular Weight
1842.96
References & Citations
[1]Siskind S, et al. TREM-1 Modulation Strategies for Sepsis. Front Immunol. 2022 Jun 15;13:907387. doi: 10.3389/fimmu.2022.907387.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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