CP-EPS8-NLS
CP-EPS8-NLS is a peptide with anti-AML property. CP-EPS8-NLS interferes with EPS8-associated signaling and exerts anti-AML activity in various AML cell types. CP-EPS8-NLS has potent antitumor activity in xenograft tumor models. CP-EPS8-NLS downregulates EPS8 expression and its downstream pathway[1].
Product Specifications
UNSPSC
12352209
Target
Complement System
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
O=C(C)NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N1[C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](CO)C(N[C@@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@H](CCCCN)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C130H249N61O29
Molecular Weight
3130.76
References & Citations
[1]Chen, Y., et al., (2018) . A synthetic cell-penetrating peptide derived from nuclear localization signal of EPS8 exerts anticancer activity against acute myeloid leukemia. Journal of experimental & clinical cancer research : CR, 37 (1), 12.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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