P53-hDM2 cyclic peptide inhibitor 16e
Selected Variant
HY-P11036
Size: 1 Each
P53-hDM2 cyclic peptide inhibitor 16e is a p53-hDM2 cell-permeable peptide inhibitor with an IC50 of 9.24 nM for hDM2. p53-hDM2 cyclic peptide inhibitor 16e can be used for cancers like breast, colorectal and cervical cancers research[1].
Product Specifications
UNSPSC
12352209
Target
MDM-2/p53
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H]2CC3=CC=C(O)C=C3)=O)CCC(O)=O)=O)CSCCCCCCSC[C@H](NC([C@@H](NC2=O)CC4=CNC5=C4C=CC=C5)=O)CNC(N[C@H](CNC(N[C@H](CNC(N)=O)C(C)C)=O)C)=O)=O)=O)[C@H](O)C)[C@H](CCCCN)NC(C)=O
Molecular Formula
C69H102N16O15S2
Molecular Weight
1459.78
References & Citations
[1]Neuville M, et al. Cell-Permeable Peptide Inhibitors of the p53-hDM2 Interaction via Foldamer Helix Mimicry and Bis-Thioether Stapling. J Med Chem. 2025 Jan 9;68 (1) :236-246.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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