Mp-4D7-pF2
Mp-4D7-pF2, a cell-penetrating bicyclic peptide, is a noncovalent SARS-CoV-2 main protease inhibitor with an IC50 of 4.51 μM. Mp-4D7-pF2 has an antiviral activity against SARS-CoV-2 with no cytotoxicity. Mp-4D7-pF2 can used for COVID-19 infections research[1].
Product Specifications
UNSPSC
12352209
Target
SARS-CoV; Virus Protease
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(N[C@@H](C(C)C)C(N[C@@H](CSC1=C(F)C(F)=C2C(F)=C1F)C(N[C@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CNC=N4)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N5[C@@H](CCC5)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CSC7=C(F)C(F)=C2C(F)=C7F)C(N8[C@@H](CCC8)C(N9[C@@H](CCC9)C(N[C@H](CC%10)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(CC%11=CC=C(C=C%11)O)NC%10=O
Molecular Formula
C88H101F8N17O19S2
Molecular Weight
1916.96
References & Citations
[1]Tan Y, et al. De Novo Discovery of a Noncovalent Cell-Penetrating Bicyclic Peptide Inhibitor Targeting SARS-CoV-2 Main Protease. J Med Chem. 2024 Nov 28;67 (22) :20258-20274.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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