Thiazoplanomicin
Thiazoplanomicin (Compound 1) is a thiazolyl peptide antibiotic. Thiazoplanomicin can be isolated from the leaf-litter actinomycete Actinoplanes sp. MM794L-181F6. Thiazoplanomicin has potent antimicrobial activities against gonococcal strains (especially drug-resistant strains) and Gram-positive bacterium with MICs of 31.2-125 and 0.5-15.6 ng/mL, respectively. Thiazoplanomicin has no antibacterial activity against E.coli. Thiazoplanomicin can be used for bacterial infections research[1].
Product Specifications
UNSPSC
12352209
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NC(C(N)=O)=O)C1=CSC(C2=NC(C3=CSC4=N3)=C(C5=NC(C(N[C@@](C(N/C(C6=NC(C(N[C@@](C7=NC=C(C(N[C@@]4([H])COC8=O)=O)S7)([H])[C@](C(O)C(OC9)=O)([H])OCC%10=C8N(O)C%11=C%10C9=CC=C%11)=O)=CS6)=C/C)=O)([H])C(C)([H])O)=O)=CS5)C=C2O)=N1
Molecular Formula
C50H39N13O16S5
Molecular Weight
1238.25
References & Citations
[1]Takehana Y, et al. Thiazoplanomicin, a new thiazolyl peptide antibiotic from the leaf-litter actinomycete Actinoplanes sp. MM794L-181F6. J Antibiot (Tokyo) . 2025 Jan;78 (1) :14-25.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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