DOTA-TMVP1446
DOTA-TMVP1446 is a VEGFR-3 targeting peptide. DOTA-TMVP1446 labeled with 68Ga accurately detectes the status of lymph node metastasis, even in micrometastatic tumors, in the B16-F10 tumor mice model. DOTA-TMVP1446 can be used as a radiotracer for cancer-metastatic sentinel lymph nodes (m-SLN) imaging[1].
Product Specifications
Product Name Alternative
DOTA-PEG4-TMVP1446
UNSPSC
12352209
Target
VEGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(CN1CCN(CCN(CCN(CC1)CC(O)=O)CC(NCCOCCOCCOCCOCCC(N[C@@H](CS)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(NCC(NCC(NCC(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC(O)=O)O
Molecular Formula
C74H134N26O28S
Molecular Weight
1868.08
References & Citations
[1]Yuan Y, et al. Identification of a Novel Vascular Endothelial Growth Factor Receptor-3-Targeting Peptide for Molecular Imaging of Metastatic Lymph Nodes. Bioconjug Chem. 2024 Nov 20;35 (11) :1843-1858.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
VEGFR3/Flt-4
Frequently Asked Questions
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