DX-236
DX-236 is a macrocyclic peptide with a binding affinity of 1.9 µM to human serum albumin (HSA) . DX-236 can fuse with HSV to prolong its circulation in vivo[1].
Product Specifications
UNSPSC
12352209
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Smiles
O=C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N6[C@@H](CCC6)C(N[C@@H](CCC(O)=O)C(NCC(NCC(NCC(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC7=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CC8=CNC9=CC=CC=C89)C(N[C@@H](CC%10=CC=C(C=C%10)O)C(N%11[C@@H](CCC%11)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC%12=CNC=N%12)C(N[C@H]7CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C
Molecular Formula
C164H223N41O47S2
Molecular Weight
3584.90
References & Citations
[1]Wong JYK, et al. Genetically encoded discovery of perfluoroaryl macrocycles that bind to albumin and exhibit extended circulation in vivo. Nat Commun. 2023 Sep 13;14 (1) :5654. doi: 10.1038/s41467-023-41427-y. Erratum in: Nat Commun. 2023 Nov 21;14 (1) :7587.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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