Tet1 peptide

Tet1 peptide (HLNILSTLWKYR) is neuron-specific ligand for GT1B gangliosides. And a cysteine is usually add to its C-terminus (which refers to HLNILSTLWKYRC (HY-P11094) ) for peptide conjugation and drug delivery reseraches.

Product Specifications

CAS Number

[270919-17-0]

UNSPSC

12352209

Target

TET Protein

Related Pathways

Epigenetics

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC4=CNC=N4)N

Molecular Formula

C73H114N20O17

Molecular Weight

1543.81

References & Citations

[1]Wang P, et al. Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease. J Control Release. 2018 Jun 10;279:220-233.|[2]Zhang Y, et al. Targeted delivery of Tet1 peptide functionalized polymersomes to the rat cochlear nerve. Int J Nanomedicine. 2012;7:1015-22.