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NG2 binding peptide

NG2 binding peptide is a short peptide that specifically recognizes NG2 proteoglycan and can be obtained by phage screening technology. NG2 binding peptide interacts with NG2 binding sites to achieve precise targeting of tumor angiogenesis in vitro and in vivo. NG2 binding peptide exhibits significant homing ability in wild-type tumor-bearing mice, but has no localization effect in NG2 knockout mice. Due to the tissue specificity of NG2 expression, NG2 binding peptide can be used in scenarios such as tumor targeted therapy, drug delivery, and molecular imaging diagnosis[1].

Product Specifications

CAS Number

[241478-23-9]

UNSPSC

12352209

Target

Others

Related Pathways

Others

Field of Research

Cancer

Smiles

O=C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CO)C(NCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](CC1=CNC=N1)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N

Molecular Formula

C40H69N15O14S

Molecular Weight

1016.13

References & Citations

[1]Burg MA, et al. NG2 proteoglycan-binding peptides target tumor neovasculature. Cancer Res. 1999 Jun 15;59 (12) :2869-74.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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