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ErbB2 peptide

ErbB2 peptide is a peptide ligand of E3 ubiquitin ligase targeting PI3K for peptide PROTACs[1].

Product Specifications

CAS Number

[325791-52-4]

UNSPSC

12352209

Target

Ligands for E3 Ligase; PI3K

Related Pathways

PI3K/Akt/mTOR; PROTAC

Field of Research

Cancer

Smiles

O=C(N1[C@@H](CCC1)C(NCC(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCSC)C(NCC(N[C@@H](C)C(N[C@@H](CS)C(N3[C@@H](CCC3)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(NCC(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN

Molecular Formula

C99H148N28O37S3

Molecular Weight

2418.59

References & Citations

[1]Sinan Ma, et al. Non-small molecule PROTACs (NSM-PROTACs) : Protein degradation kaleidoscope. Acta Pharm Sin B. 2022 Jul;12 (7) :2990-3005.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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