Ac-AAVALLPAVLLALLAPVAD-CHO (TFA)

Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a composite of Ac-VAD-CHO. Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a non-selective caspase inhibitor as well as a cell permeable hydrophobic sequence derived from K-FGF[1][2].

Product Specifications

UNSPSC

12352209

Target

Caspase

Related Pathways

Apoptosis

Field of Research

Others

Smiles

O=C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C.O=C(O)C(F)(F)F

Molecular Formula

C90H152F3N19O24

Molecular Weight

1941.28

References & Citations

[1]Kim, J. Y., & Park, J. H. (2003) . ROS-dependent caspase-9 activation in hypoxic cell death. FEBS letters, 549 (1-3), 94–98. |[2]Lin, Y. Z., et al., (1995) . Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. The Journal of biological chemistry, 270 (24), 14255–14258.