Fulipiftide

Fulipiftide is a short peptide derived from pigment epithelium-derived factor (PEDF) . Fulipiftide induces the expansion of nuclear stem cell factor +TSPC by activating ERK2 and STAT3 signaling pathways. Fulipiftide has anti-inflammatory activity and can be used in the study of acute tendon injury[1][2].

Product Specifications

CAS Number

[2868985-56-0]

Product Name Alternative

PSP 29-mer, anti-inflammatory peptide

UNSPSC

12352209

Target

ERK; STAT

Related Pathways

JAK/STAT Signaling; MAPK/ERK Pathway; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Purity

99.38

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C[C@@H](O)[C@@H](C(N)=O)NC(CNC([C@H](CC1=CN=CN1)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H]2N(CCC2)C([C@H](CO)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCC(O)=O)NC([C@H](C)NC(CNC([C@H](CC(C)C)NC([C@H](CO)NC(C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)CC5=CC=C(C=C5)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C144H227N41O47

Molecular Weight

3284.59

References & Citations

[1]WHO. International Nonproprietary Names for Pharmaceutical Substances (INN), Proposed International Nonproprietary Names: List 132. WHO Drug Information, Vol. 38 , No. 4, 2024.|[2]Ho TC, et al. PEDF-derived peptide promotes tendon regeneration through its mitogenic effect on tendon stem/progenitor cells. Stem Cell Res Ther. 2019 Jan 3;10 (1) :2.