PD-L1 inhibitory peptide
PD-L1 inhibitory peptide is an inhibitor peptide targeting programmed cell death ligand 1 (PD-L1) . PD-L1 inhibitory peptide binds to PD-L1, relieving immunosuppression and restoring the antitumor activity of T cells. PD-L1 inhibitory peptide is promising for research of cancers[1][2].
Product Specifications
CAS Number
1931111-41-9
UNSPSC
12352209
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology
Smiles
OC(CN1C2=CC=CC=C2C(C[C@H]3C(N([C@H](C(N([C@H](C(N[C@H](C(N[C@@H](CSCC(N[C@H](C(N([C@H](C(N[C@H](C(N4[C@](CCC4)([H])C(N[C@H](C(N[C@H](C(N5[C@](C[C@H](C5)O)([H])C(N[C@H](C(N[C@H](C(N3)=O)CCN)=O)CC6=CNC7=CC=CC=C67)=O)=O)CC(C)C)=O)CN)=O)=O)CC(N)=O)=O)C)C)=O)CC8=CC=C(C=C8)O)=O)C(NCC(N[C@H](C(O)=O)CC#C)=O)=O)=O)CC(C)C)=O)CCCC)C)=O)CCCC)C)=O)=C1)=O
Molecular Formula
C96H135N21O23S
Molecular Weight
1983.29
References & Citations
[1]Shindo Y, et al. Anti-PD-L1 peptide improves survival in sepsis[J]. Journal of Surgical Research, 2017, 208: 33-39.|[2]Boohaker RJ, et al. Rational design and development of a peptide inhibitor for the PD-1/PD-L1 interaction. Cancer Lett. 2018 Oct 10;434:11-21.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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