FAP targeting peptide for FXX489

FAP targeting peptide for FXX489 is the polypeptide part of Unlabeled FXX489 (HY-P10944) . Unlabeled FXX489 is a fibroblast activation protein (FAP) -targeting ligand[1].

Product Specifications

CAS Number

[3076328-74-7]

UNSPSC

12352209

Target

FAP; Radionuclide-Drug Conjugates (RDCs)

Related Pathways

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.49

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NCC1=CC=C(C[C@H](NC([C@H](CC2=CC=CC=C2)N(C)C(CNC(CNC([C@H]3CCCN3C([C@H](CC(O)=O)NC([C@H](CCCCNC(N4CCN(CC(O)=O)CC4)=O)NC(CN5)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CCCCCC)C(N[C@@H](CC6=CNC7=C6C=CC=C7)C5=O)=O)=O)C=C1

Molecular Formula

C67H91N15O15

Molecular Weight

1346.53

References & Citations

[1]Ravit Geva, et al. Abstract CT112: Phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of FXX489 ([177Lu]Lu-NNS309) in patients with pancreatic, lung, breast and colorectal cancers. Cancer Res (2025) 85 (8_Supplement_2) : CT112.