APO-15
APO-15 is a fluorogenic imaging agent targeting phosphatidylserine (PS) exposed on the cell membrane of apoptotic cells. APO-15 can selectively bind to apoptotic cells, enabling staining and imaging of apoptotic cells in a calcium-independent and wash-free manner. APO-15 is promising for research of inflammatory diseases and cancers[1].
Product Specifications
CAS Number
3051946-11-0
UNSPSC
12352209
Target
Ser/Thr Kinase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Purity
99.45
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
Molecular Formula
C70H85BF2N16O7
Molecular Weight
1311.33
References & Citations
[1]Barth ND, et al. A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis. Nat Commun. 2020 Aug 12;11 (1) :4027.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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