CGN peptide
CGN peptide is a 13 amino acid peptide composed of D-amino acids, referred to as CGN peptide. CGN peptide is the retro-inverso isomer of the l-peptide TGN (TGNYKALHPHNG) and can deliver siRNA to the blood-brain barrier (BBB) . CGN peptide can be used in Alzheimer's disease (AD) research[1].
Product Specifications
CAS Number
[2421211-40-5]
UNSPSC
12352209
Target
Small Interfering RNA (siRNA)
Related Pathways
Epigenetics
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(NCC(N[C@H](CC(N)=O)C(N[C@H](CC1=CNC=N1)C(N2[C@H](CCC2)C(N[C@H](CC3=CNC=N3)C(N[C@H](CC(C)C)C(N[C@H](C)C(N[C@H](CCCCN)C(N[C@H](CC4=CC=C(C=C4)O)C(N[C@H](CC(N)=O)C(NCC(N[C@H]([C@@H](O)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](CS)N
Molecular Formula
C60H90N20O18S
Molecular Weight
1411.54
References & Citations
[1]Zheng X, et al. A hybrid siRNA delivery complex for enhanced brain penetration and precise amyloid plaque targeting in Alzheimer's disease mice. Acta Biomater. 2017 Feb;49:388-401.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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