Wrwycr-NH2 (TFA)
Wrwycr-NH2 (TFA) is a peptide. wrwycr-NH2 (TFA) is cytotoxic to multiple cancer cells, can induce DNA damage and cell cycle arrest, but does not induce endoplasmic reticulum stress. wrwycr-NH2 (TFA) has anti-tumor activity, and it shows better efficacy when used in combination with DNA-damaging agents[1].
Product Specifications
UNSPSC
12352209
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.18
Smiles
O=C(N[C@H](CCCNC(N)=N)C(N[C@H](CC1=CNC2=CC=CC=C12)C(N[C@H](CC3=CC=C(C=C3)O)C(N[C@H](CS)C(N[C@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)[C@@H](CC4=CNC5=CC=CC=C45)N.O=C(C(F)(F)F)O.[x]
Molecular Formula
C46H61N15O7S.xC2HF3O2
Molecular Weight
968.14 (free base)
References & Citations
[1]Dey M, et al. Tumor cell death mediated by peptides that recognize branched intermediates of DNA replication and repair. PLoS One. 2013 Nov 14;8 (11) :e78751.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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