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(Z) -Zolucatetide

(Z) -Zolucatetide ((Z) -FOG-001; I-67), a structural isomer of Zolucatetide (HY-P10925), is a potent β-catenin inhibitor with an IC50 of [1].

Product Specifications

Product Name Alternative

(Z) -FOG-001; I-67

UNSPSC

12352209

Target

β-catenin

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

98.19

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CC1=CSC2=C1C=CC=C2)C(N[C@@H](CCC(NCCCC[C@H](NC([C@@H](NC([C@H](C)NC(C(C)(C)NC([C@H](CC3=CC=CC(C(O)=O)=C3)NC([C@@H](N4)CC(O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)C6=O)=O)C(N[C@H](C(N)=O)C)=O)=O)[C@H](CC7=CSC=C7)NC([C@@]8(CCN(C(OCCC/C=C\CCC[C@](NC([C@H](CC(C)(C)C)NC([C@H](CC(O)=O)N9)=O)=O)(CCC/C=C\C[C@]%10(CCCN%10C(C)=O)C9=O)C4=O)=O)C8)N6)=O

Molecular Formula

C102H134N18O25S2

Molecular Weight

2076.39

References & Citations

[1]Brian Halbert WHITE, et al. Stapled peptides and methods thereof. WO2022261257A1.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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